Past Symposia

Symposium Information

The 13th annual GRASP NMR symposium was held virtually, via Zoom, on October 9-10, 2020

Plenary Speakers

Ad Bax originally planned to attend as plenary speaker for GRASP 2020. However, because of the pandemic,his visit has been postponed to a later date when our symposium can be held in person again.

Speakers

Amritangshu Chakravarty
PhD Candidate
Department of Molecular Biosciences
University of Kansas
“Identification and Characterization of the Binding of Novel Small Molecules to Salmonella Tip Protein SipD”

Tahnee J. Dening, PhD
Postdoctoral Researcher
Department of Pharmaceutical Chemistry
University of Kansas
“Understanding Interactions of a Peptide Drug with Bile Salts under Simulated Gastrointestinal Conditions via NMR Spectroscopy”

Catherine Eichhorn, PhD
Assistant Professor
Department of Chemistry
University of Nebraska-Lincoln
“Structural basis for Larp7 recognition of the noncoding 7SK RNA: an NMR-guided approach”

Thomas Gremminger
Graduate Student
Department of Biochemistry
University of Missouri
“RNA structure in reverse transcription initiation is important to maintain viral RNA integrity”

Wyel Halimeh
Undergraduate Student
Department of Chemistry
Wichita State University
“Dependence of Proline Isomerization on the Kinetics of Folding of Anthrax Lethal Factor”

Xiao Heng, PhD
Associate Professor
Department of Biochemistry
University of Missouri
“Structural studies of the HIV-1 PBS-segment RNA: insights into virus:host interactions in promoting viral infectivity”

Balabhadra Khatiwada
Graduate Student
Department of Chemistry
Iowa State University
"Investigating the conformational dynamics in human RNA demethylase FTO”

Nicholas Reiter, PhD
Assistant Professor
Department of Chemistry
Marquette University
“NMR-based structural biology approaches to understand molecular recognition and conformational dynamics within large protein-nucleic acid systems”

Thomas Schmidt, PhD
Post-Doctoral Fellow
Laboratory of Chemical Physics
National Institutes of Health
“Probing the Maturation of heterodimeric HIV-1 Reverse Transcriptase from its homodimeric precursor by Double Electron‐Electron Resonance EPR Spectroscopy”

Symposium Information

The 12th annual GRASP NMR symposium was held on November 22 - 23, 2019 at the University of Kansas

Plenary Speaker

Dr. Christopher Jaroniec
Professor of Chemistry & Biochemistry
Vice Chair for Research and Administration
Ohio State University
"Molecular Mechanisms of Prion and Amyloid Propagation Explored by Solid-
State NMR Spectroscopy”

Speakers

Amy Andreotti, PhD
University Professor
Roy J. Carver Endowed Chair Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology
Iowa State University
“Elucidating the molecular switches that control signaling of immune kinases”

James Bann, PhD
Associate Professor
Department of Biochemistry
Wichita State University
“¹⁹F-NMR studies of the anthrax protective antigen prepore and pore using site-specific labeling and uniform labeling”

Pallavi Guha Biswas
Graduate Student
Department of Molecular Biosciences
University of Kansas
“EPR reveals the structural dynamics of an unfolded protein in Yersinia Pathogenesis”

Alexandra Born
PhD Canditate
Department of Biochemistry and Molecular Genetics
University of Colorado Denver
“eNOEs and DEER-EPR to Elucidate Allostery and Dynamics in Pin1”

Roger E. Koeppe II
Distinguished Professor
Department of Chemistry and Biochemistry
University of Arkansas
“NMR Benchmarks for Membrane Biophysics: What are arginine and glutamic acid doing in lipid bilayers?”

Gary Meints
Associate Professor
Department of Chemistry
Missouri State University
“Alteration of BI/BII Backbone Conformations in DNA by Mismatches and Single Base Lesions”

Smita Mohanty
Professor
Department of Chemistry
Oklahoma State University
“Congenital Disorders Of Glycosylation: Mechanism Of Oligosaccharyltransfearse Function”

Trang Nguyen
Graduate Student
Department of Chemistry
Iowa State University
“Identification of allosteric inhibitors of Enzyme I by NMR-based fragment screening”

Robert Powers
Professor
Department of Chemistry
University of Nebraska-Lincoln
“A Combined NMR and MS Metabolomics Approach to Study Neurodegenerative Diseases”

Aaron J. Rudeen
Graduate Student
Department of Molecular Biosciences
University of Kansas
“A domain of Adenomatous polyposis coli retained by colon tumors is intrinsically disordered, and can bind three β-catenin molecules”

Steven Van Doren
Professor
Department of Biochemistry
University of Missouri
"Biomolecular Associations by NMR: i. Automatic Quantification and ii. Novel and Switchable Modes of Membrane Binding”

Vincenzo Venditti
Assistant Professor
Department of Chemistry
Iowa State University
"Conformational disorder in regulation of enzymatic catalysis”

Benjamin J. Wylie, PhD
Assistant Professor
Department of Chemistry and Biochemistry
Texas Tech University
“Solid-state NMR studies of Kir channel-lipid interactions and the fibrillation of functional amyloids in the epididymis”

Awardees

Best Student Talk Award

Trang Nguyen, graduate student in chemistry from Iowa State University, Ames, IA

Best Poster Presentation

Lynn Schrag, graduate student in the Department of Biochemistry and Molecular Biophysics at Kansas State University, Manhattan, KS

Megan N. Westwood, graduate student in the Department of Chemistry at Missouri State University, Springfield, MO

2018 Speakers

Plenary Speaker

Rafael Brüschweiler
Professor, Ohio Research Scholar, Department of Chemistry and Biochemistry, Ohio State University, Columbus, OH
"Advanced complex mixture analysis by NMR and NMR/MS for metabolomics"

Invited Speakers:

Gabriel Cook, Assistant Professor, Department of Chemistry, Oklahoma State University, Stillwater, OK
"Using NMR to Monitor Post-translational Modification"

Elan Eisenmesser, Associate Professor, Molecular Biology Program, School of Medicine, University of Colorado Anschutz Campus, Aurora, CO
"Protein dynamics drives redox regulation"

Nathan Oyler, Associate Professor, Department of Chemistry,University of Missouri-Kansas City, Kansas City, MO
"Using NMR to Quantify Drug Release from Pharmaceutical Formulations"

Om Prakash, Professor, Department of Biochemistry and Molecular Biophysics, Director, NMR Facility, Kansas State University, Manhattan, KS
"NMR Studies of a Novel Family of Neutrophil Serine Proteases (NSP) Inhibitors: Toward Understandingthe Structural Basis for Complement Inhibition by Staphylococcus aureus Innate Immune Evaision Proteins"

Julien Roche, Assistant Professor, Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA
"From IDP to IDR in MFP"

Beat Vogeli, Assistant Professor, School of Medicine,Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Campus, Aurora, CO
"Sub-ångström resolution in RNA, protein disorder in dynein-dependent cargo transport"

2018 Awardees

Best Student Talk Award

Jeffrey Purslow, graduate student in the Department of Chemistry at Iowa State University, Ames, IA

Best Poster Presentation

Rochelle Dotas, graduate student in the Department of Chemistry at Iowa State University, Ames, IA

2017 Speakers

Plenary Speaker

Dorothee Kern
Professor of Biochemistry, Investigator, Howard Hughes Medical Institute, Brandeis University, Waltham, MA
"NMR at its Best: Evolution of Protein Dynamics over 3.5 Billion Years and New Strategies for Drug Design"

Invited Speakers:

Paul Adams, Associate Professor of Biochemistry, Cellular and Molecular Biology, University of Arkansas, Fayetteville, AR
"Biochemical and Biophysical Approaches to Characterize the Molecular Basis of Abnormal Cell Signaling Function Involving Ras-Related Proteins"

Ernesto Fuentes, Associate Professor of Biochemistry, University of Iowa, Carver College of Medicine, Iowa City, IA
"Insights into Molecular Recognition from PDZ Domains"

Justin Lorieau, Assistant Professor of Chemistry, University of Illinois at Chicago, Chicago, IL
"Hybrid NMR: A Combination of Solution and Solid-State NMR"

Aaron Rossini, Assistant Professor of Chemistry, Iowa State University, Ames, IA
"Sensitizing Solid-State NMR Spectroscopy for the Characterization of Pure and Formulated Pharmaceuticals"

2017 Awardees

Best Student Talk Award

Faith Scott, graduate student in chemistry from Washington University, St. Louis, St. Louis, MO.

Best Poster Presentation

Jeffrey Purslow, graduate student in chemistry from Iowa State University, Ames, IA.

2016 Speakers

Plenary Speaker

John Markley
Steenbock Professor, Biomolecular Structure, Director of the National Magnetic Resonance Facility at Madison (NMRFAM) and BioMagResBank (BMRB), Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin
"Conformational States and Interactions of Proteins Involved in the Biogenesis of Iron-Sulfur Proteins"

Invited Speakers:

Justin Douglas, NMR Laboratory Director, University of Kansas, Lawrence, Kansas
"Automated structure verification in an academic synthetic chemistry workflow"

John Laity, Associate Professor, School of Biological Sciences, Division of Cell Biology and Biophysics, University of Missouri at Kansas City, Kansas City, Missouri
"Probing the Functional Roles of MTF-1 and p300 in Mammalian Zn(II) Homeostasis: NMR and Calorimetric Studies Implicate Zn(II) Binding Heterogeneity in the p300-TAZ2 and MTF-1 DNA Binding Domains as Key Determinants"

Katie Mitchell-Koch, Assistant Professor, Department of Chemistry, Wichita State University, Wichita, Kansas
"Connections between electronic structure, protein environment, and fluorine chemical shifts"

Steven R. Van Doren, Professor, Department of Biochemistry, University of Missouri at Columbia, Columbia, Missouri
"Transient interactions of Metalloproteinases with Bilayers by Paramagnetic NMR"

Vincenzo Venditti, Assistant Professor, Department of Chemistry, Iowa State University, Ames, Iowa
"Versatile dynamics in the C-terminal domain of bacterial Enzyme I"

Liliya Vugmeyster, Assistant Professor, Department of Chemistry, University of Colorado-Denver, Denver, Colorado
"Dynamics and solvation of amyloid Abeta"

Erik R.P. Zuiderweg, Professor, Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan
"Diffusive and tethered complexes by NMR"

2016 Awardees

Best Student Talk Award

Jonathan Ellis, graduate student from Wichita State University, Wichita, KS

Best Poster Presentation

Jia Xu and Samantha Brady, both from University of Missouri-Columbia, Columbia, MO.

2015 Speakers

Plenary Speaker

Tatiana Kutateladze
Professor, Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO
"Molecular mechanisms of the epigenetic regulation"

Invited Speakers:

Moriah Beck, Assistant Professor, Department of Chemistry, Wichita State University, Wichita, KS
"Cell motility: integrating protein structure and flexibility with cytoskeletal dynamics"

Xiao Heng, Assistant Professor, Department of Biochemistry, University of Missouri-Columbia, Columbia, MO
"NMR studies of the conserved 3’X tail of the Hepatitis C virus genome RNA"

Adina Kilpatrick, Assistant Professor, Department of Physics, Drake University, Des Moines, IA
"Thermodynamic and structural analysis of calmodulin interaction with the skeletal muscle ryanodine receptor"

Jed Lampe, Assistant Professor, Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS
"Exploring the ligand binding conformational sub-space of cytochrome P450 enzymes utilizing a combined approach of NMR, fluorescence, and x-ray crystallography"

Smita Mohanty, Associate Professor, Department of Chemistry Oklahoma State University, Stillwater, OK
"Congenital Disorders of Glycosylation: Mechanisms of Oligosccharyl Transferase Function "

Robert Powers, Professor, Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE
"Metabolomics and drug discovery"

Susan Schroeder, Associate Professor, Department of Microbiology and Plant Biology, University of Oklahoma, Norman, OK
"Structures, Dynamics, and Metal Ion Binding in Prohead RNA"

2014 Speakers

Invited Speakers:

Arthur Pardi, University of Colorado, Boulder, Department of Chemistry and Biochemistry, Boulder, CO
"Changes in Protein Dynamics in the Active and Inactive Forms of the MAP Kinase ERK2"

Adam Barb, Assistant Professor, Iowa State University, Department of Biochemistry, Biophysics & Molecular Biology, Ames, IA
"Restricted Motion of the Conserved Immunoglobulin G1 N-glycan is Essential for Efficient FcγRIIIa Binding"

Sorin Luca, Assistant Professor, University of Nebraska Medical Center, Department of Pharmaceutical Sciences, College of Pharmacy, Omaha, NE
"Structural and Functional Studies of the Membrane Scaffolding Protein caveolin-1"

Boyd Goodson, Professor, Southern Illinois University Carbondale, Department of Chemistry and Biochemistry, Carbondale, IL
"Enhancing NMR and MRI with Hyperpolarized Xenon and Signal Amplification by Reversible Exchange"

Alexander Barnes, Assistant Professor, Washington University in St. Louis, Department of Chemistry, St. Louis, MO
"Dynamic Nuclear Polarization Development for Membrane Protein Ligand Structure"

Catherine Musselman, Assistant Professor, University of Iowa, Department of Biochemistry, Carver College of Medicine, Iowa City, IA
"Using NMR to Study Multivalent Interactions with Modified Nucleosomes"

Gabriel Cook, Assistant Professor, Oklahoma State University, Department of Chemistry, Stillwater, OK
"The Structure of Hepatitis C Virus Membrane Protein p7 in Bilayers by NMR Spectroscopy"

Xiaolan Yao, Assistant Professor, University of Missouri at Kansas City, School of Biological Sciences, Kansas City, MO
"Structural and Biochemical Investigation of Ceramide Transfer Protein Functional Regulation"